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How LSD Actually Works
It started as a fungus on rye bread. Then a chemist, the CIA, Congress and psychiatry each found out what it does to a brain.
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LSD
LSD is a powerful semisynthetic psychedelic drug derived from ergot, a fungus that grows on rye.
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Ergotism
Ergotism is toxic poisoning caused by eating fungus-infected rye or grain.
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5-HT2A receptor
The 5-HT2A receptor is the primary excitatory serotonin receptor in the brain and the main docking target for psychedelic drugs like LSD.
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Default Mode Network
The default mode network is a coordinated set of brain regions that fires up when you are not focused on the outside world.
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MKUltra
MKUltra was a covert, illegal human experimentation program run by the CIA from 1953 to 1972 to test mind control and truth serums.
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Controlled Substances Act
The Controlled Substances Act established the federal five-tier drug scheduling system and unified US drug regulation under the DEA and FDA.
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Psychedelic therapy
Psychedelic therapy is the use of psychedelic substances under professional supervision to treat mental health disorders.