Medicine
89 ideas, each explained on one page with a 60-second lesson you can play right there.
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Allostatic load
Allostatic load is the cumulative physical wear and tear on your body caused by chronic or repeated stress.
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AMP-activated protein kinase
AMP-activated protein kinase (AMPK) is an enzyme inside cells that acts as a low-energy sensor.
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Amyloid beta
Amyloid beta is a small protein fragment naturally produced and released by brain cells every day.
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Angiogenesis
Angiogenesis is the growth of new blood vessels from pre-existing ones.
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Antibody
An antibody is a specialized protein produced by immune cells to identify and latch onto foreign invaders like viruses and bacteria.
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Antibody-dependent cellular cytotoxicity
Antibody-dependent cellular cytotoxicity uses antibodies to guide immune cells like natural killer cells to destroy infected or cancerous cells.
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Antigen
An antigen is any molecule that can latch onto a specific immune receptor or antibody, acting like a chemical identifier.
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Apoptosis
Apoptosis is programmed cell death, a built-in biological routine where an unneeded or damaged cell systematically destroys itself.
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Assay
An assay is a laboratory test that detects or measures a specific target substance, called an analyte, in a sample.
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Autophagy
Autophagy is the cell's waste recycling system.
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Avoidant coping
Avoidant coping reduces stress by evading a problem rather than fixing it, bringing immediate relief at the cost of compounding future damage.
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Basal ganglia
The basal ganglia are a group of interconnected structures deep beneath the cerebral cortex.
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Behavioral activation
Behavioral activation is a form of psychotherapy that treats depression by scheduling specific, rewarding activities into a person's routine.
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Behavioral addiction
Behavioral addiction is a compulsion to repeat a rewarding action despite real harm, sharing the same brain adaptations as drug addiction.
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Burnout (psychology)
Occupational burnout stems from unmanaged workplace stress.
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Calorie restriction
Calorie restriction lowers energy intake while maintaining essential nutrients, shifting cellular resources toward repair and metabolic health.
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CAR T cell
A CAR T cell is a patient's own white blood cell that has been genetically modified in a laboratory to hunt and destroy cancer cells.
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Cell Culture
Cell culture is the process of growing living cells outside their natural organism inside controlled laboratory vessels.
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Checkpoint inhibitor
Cancer drugs called checkpoint inhibitors block off-switches on T cells, freeing the immune system to attack tumors.
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Chemotherapy
Chemotherapy is a systemic cancer treatment that uses drugs to disrupt cell division and trigger cell death.
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Chronotype
A chronotype is a person's natural biological tendency to sleep and be active at specific times during a 24-hour day.
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Circadian Rhythm
Circadian rhythms are roughly 24-hour internal biological cycles.
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Cognitive Behavioral Therapy (CBT)
Cognitive behavioral therapy treats automatic negative thoughts as unverified hypotheses, combining cognitive reframing with new behavioral habits.
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Cognitive behavioral therapy for insomnia
Cognitive behavioral therapy for insomnia is the first-line treatment for chronic insomnia, relying on sleep restriction and stimulus control.
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Cognitive Distortions
A cognitive distortion is an exaggerated or irrational thought pattern that causes you to perceive reality inaccurately.
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Cognitive reframing
Cognitive reframing is a technique where you identify and change the way you view situations, thoughts, or emotions.
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Complement System
The complement system is a network of about 50 blood proteins that automatically attack foreign invaders and clear damaged cells.
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Creatine
Creatine is an organic compound that your body uses to rapidly recycle ATP, the molecule cells consume for energy.
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CRISPR
CRISPR is a microbial defense mechanism that stores virus DNA fragments and guides Cas enzymes to cut matching genetic sequences.
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Cytotoxicity
Cytotoxicity is the ability of a substance to damage or kill living cells.
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Defence mechanism
Defence mechanisms are unconscious psychological tactics that protect the mind from anxiety and maintain emotional homeostasis.
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Dementia Dementia is an umbrella term for a progressive decline in mental abilities caused by physical damage to the brain, which interferes with daily life.
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DNA Sequencing
DNA sequencing determines the precise order of bases in genetic material, shrinking full-genome reads from thirteen years to under a day.
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Dopamine
Dopamine is a chemical messenger that nerve cells use to communicate with one another.
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Doppler Effect
The Doppler effect changes the observed pitch or frequency of waves when a source and observer move relative to each other.
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Dose–response relationship
A dose–response relationship is the pattern showing how a living system reacts to different amounts of a substance or stressor over time.
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Enteric nervous system
The enteric nervous system is a mesh of 500 million neurons lining your digestive tract that runs your digestion.
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Enteroendocrine cell
Enteroendocrine cells are hormone-producing cells scattered throughout the lining of the stomach, intestines, and pancreas.
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Exposure therapy
Exposure therapy treats anxiety by confronting fear triggers without escaping, helping the brain learn that the feared outcome will not occur.
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Gene Therapy
Gene therapy is a medical technique that treats disease by directly altering the genetic material inside a patient's living cells.
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Gut Microbiome
The gut microbiome contains 10 to 100 trillion microbes that ferment fiber, make vitamins, and influence mood via the gut-brain axis.
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Habit reversal training
Habit reversal training treats tics, hair pulling, and nail biting by teaching a physical action that blocks the repetitive urge.
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IC50
IC50 measures how much of a drug is needed to inhibit a biological target by 50 percent, acting as a core metric for inhibitor potency.
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Immune Memory
How specialized memory B and T cells recognize returning pathogens to eliminate them before they can cause illness.
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Immunology
Immunology is the branch of biology and medicine that studies how immune systems protect organisms from disease.
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Insomnia
Insomnia is a sleep disorder where a person struggles to fall asleep or stay asleep for as long as needed.
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Killer T Cells
Killer T cells are white blood cells that hunt and destroy infected or cancerous cells by recognizing antigens displayed on MHC molecules.
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Lactate dehydrogenase
Lactate dehydrogenase is an enzyme found in almost all living cells that converts pyruvate into lactate and back again.
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Major histocompatibility complex
Learn how the Major Histocompatibility Complex (MHC) presents protein fragments on cell surfaces to help T cells detect viruses and cancers.
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Melatonin
Melatonin is a hormone produced in the brain that tells the body when it is dark outside.
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Metastasis
Metastasis is the spread of cancer cells from a primary tumor to distant organs through the bloodstream or lymphatic system.
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Metformin
Metformin is a medication taken by mouth to lower blood sugar in people with type 2 diabetes.
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mTOR
mTOR, or mechanistic target of rapamycin, is an enzyme inside your cells that acts as a master growth switch.
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Muscle Hypertrophy
Muscle hypertrophy is the enlargement of skeletal muscle caused by individual muscle cells growing thicker rather than multiplying.
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Muscle Soreness
Delayed onset muscle soreness comes from lengthening muscles under load, not lactic acid.
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Myenteric plexus
The myenteric plexus is a mesh-like network of nerve cells embedded between the muscle layers of your digestive tract.
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Myosatellite cell
A myosatellite cell is a dormant stem cell nestled against the outer edge of a skeletal muscle fiber.
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Narcissistic personality disorder
Narcissistic personality disorder is a psychiatric condition defined by grandiosity, low empathy, and impaired relationships across 256 trait combinations.
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Natural killer cell
Natural killer cells are white blood cells that destroy tumor and virus-infected cells lacking normal MHC class I identity markers.
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Necrosis
Necrosis is the premature, violent death of cells from trauma or infection.
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Oncogene
An oncogene is a mutated or overactive gene that has the potential to cause cancer.
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Oxytocin
Oxytocin is a peptide hormone, a small chemical messenger made of amino acids, produced in the brain's hypothalamus.
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P53
P53 is a protein that acts as a quality control inspector inside your cells, binding to DNA to control which genes get turned on.
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Piperine
Piperine is a plant compound known as an alkaloid that gives black and long pepper their pungent bite.
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Polymerase Chain Reaction
Polymerase Chain Reaction (PCR) is a laboratory method that rapidly makes billions of copies of a specific piece of DNA.
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Prion
A prion is an infectious misfolded protein that forces healthy proteins of the same type to fold into its own abnormal shape.
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Progressive overload
Progressive overload is the training principle of gradually increasing the stress placed on your muscles and nervous system.
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Proteostasis
Proteostasis is the cell's system for balancing the creation, folding, and destruction of all its proteins.
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Psychoanalysis
Psychoanalysis is a talk therapy and theory of mind founded by Sigmund Freud to uncover unconscious drives, defense mechanisms, and resistance.
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Psychological stress
Psychological stress is a reaction to perceived demands.
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Psychotherapy
Psychotherapy uses psychological methods to improve mental health.
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Rapamycin Rapamycin is a bacterial compound that inhibits mTOR, halts cell division, stops transplant rejection, and is studied for extending lifespan.
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Sarcopenia
Sarcopenia is the progressive loss of skeletal muscle mass, strength, and function that happens with aging or prolonged immobility.
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Serotonin
Serotonin is a chemical messenger that nerve cells use to communicate with each other and with the rest of the body.
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Sigmund Freud
Sigmund Freud founded psychoanalysis, explaining how unconscious desires, dreams, and slips of the tongue shape human behavior.
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Single-chain variable fragment
A single-chain variable fragment is an engineered fusion protein that links the binding tips of an antibody into a compact sensor.
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Sleep debt
Sleep debt is the cumulative effect of not getting enough sleep over days or weeks.
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Slow-Wave Sleep
Slow-wave sleep is the deepest stage of non-REM sleep, defined by large delta waves that help the brain consolidate declarative memories.
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Stress Hormone
A stress hormone is a chemical signal released by endocrine glands to adjust your body during times of threat.
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Stress Management
Stress management uses psychological techniques and physical interventions to reduce chronic stress and prevent health decline.
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T cell
Learn what T cells are, how they develop in the thymus, and how killer and helper T cells coordinate specific immune defenses.
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Tau protein
Tau protein stabilizes the internal skeleton of nerve cells, but clumps into neurofibrillary tangles during dementia and Alzheimer's disease.
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Therapeutic Window
The therapeutic window is the specific range of drug doses that effectively treats an illness without causing dangerous toxic side effects.
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Transference
Transference happens when a person unconsciously redirects feelings, expectations, or desires from past relationships onto someone in the present.
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TRPV1 Receptors
TRPV1 receptors are ion channels in sensory nerve cells that detect scalding heat, acids, and pungent chemicals like capsaicin.
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Tumor suppressor gene
A tumor suppressor gene is a stretch of DNA that produces proteins to control cell division and stop abnormal cell growth.
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Vagus nerve
The vagus nerve is the longest cranial nerve in your body, running from your brainstem down into your chest and abdomen.
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Viral vector
A viral vector is a modified virus stripped of its disease-causing parts and used to deliver genetic material into living cells.
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Work–life balance
Work–life balance is the equilibrium between a person's job and their personal life, including family, leisure, and health.